Insulin resistance

(deactivated member)
on 2/18/10 11:14 am
Just wondering if anyone has been diagnosed with insulin resistance and taking glucophage prior to surgery? If so, after the surgery how well have things been going for you in regards to weight loss? Are you no longer in need of the glucophage?

Thanks
Mishelle R.
on 2/18/10 11:32 am
Typically that is what type 2 diabetes is insulin resistancy. The Body is not allowing the insulin to get into the cells. Not enough recepters, or something to that effect. Often times folks can get out of the hospital no longer needing medications after surgery. I know for me, I was insulin resistant taking about 130 units of insulin, now post op I'm avg about 40.  I'm type 1 meaning I'm insulin dependant.



Type 1 diabetic for 25 years - pumping for 12 years.

SherryA
on 2/18/10 12:25 pm, edited 2/18/10 12:26 pm
I am insulin resistant and I took Fortamet, which is a more gastric friendly version of Glucophage.  I also took several other oral diabetic meds.  After surgery my bs was in the 200's.  It took 2-3 weeks for it to calm down.  I took insulin on a sliding scale, but have not taken anything since about my my 3 week.  My bs is still running on avg. 140-160 without any meds, which isn't really all that bad considering it ran that with meds prior to surgery.  So I am trying a new med Onglyza for a few weeks and see how it goes.  I tend to have pretty bad side effects to diabetic meds.  So if it starts causing me problems I will stop taking it.  My doc is ok with my bs, but we are trying to acheive a little more control.  I don't handle Glucophage well and Fortamet has an enteric coating so I cannot take that.  Not to mention it is a large pill.  So that wasn't an option for me after surgery. 
                    
(deactivated member)
on 2/18/10 1:06 pm
Thank you for your responses. I am not sure what you guys mean when you are talking numbers, units and bs. Luckily I do not have diabetes but have the metabolic disorder of insulin resistance. I am currently taking Glumetza which is a special coded form of glucophage. I have been told that if I have the surgery I will no longer have to take the pills. If I don't have the surgery then I will be on these pills the rest of my life just to maintain my weight.
Lori K.
on 2/19/10 2:43 am - Spokane, WA
They are responding about their BS( blood sugar) or blood glucose #'s, as they must be diabetic, and the units are the dosages of insulin they had to take to keep their bs(blood sugars) at a normal range.
I hope somone with Metabolic Syndrome, Hyperinsulism does respond.  I pasted you over on the diabetic forum as well.

Have a great Day!
Lori   <><  
Ht.  5' 5 1/2"
HW / Pre-op SW  / CW /  MY 1st GW / 2nd GW/ Surg.GW FinalGW   
                   
272 /  255   /  246 / 166/182(29bmi)/ 172(81%EWL)/ 163  /152 (24.8BMI)    
Success is the sum of small efforts, repeated day in and day out.   Robert Collier
          
Ro Smiley
on 2/19/10 5:17 am, edited 2/19/10 5:18 am - Charlotte, NC
Prir to surgery, i was diagnosed with PCOS, which has an insulance resistance componant) and was taking 3000mg of Glucophage daily.  I did not have Type II Diabetes, though, just insulin resistance.  Post-op, my surgeon told me that I would not need to take the Glucophage anymore, so I stopped (literally immediately post op).  I lost exactly 100 lbs w/i the first year (from 255.5 to 155.5.  I started regaining weight about 2.5 yrs post op.  Abouta year ago, i went an had complete bloodwork done, including hormone levels.  Cortisol levels out or whack can be indicative of active PCOS and insulin resistance. 


My primary care doctor (who happens to be an endocrinologist) put me back on the Glucophage and has told me that I will likely need to remain on Glucophage as a lifelong maintenance drug.  I do not think that I was gaining weight just because I wasn't on the Glucophage, though--i was definately making bad food choices.  I have since lost all the gained weight and am now at an all time low for me (hovering between 149-152).  I do think that getting back on the Glucophage has helped me lose the weigh that I regained more easily, but returning to smart food choices and daily exercise also played a role.  Also, there have been a few times where I have run out of Glucophage and it has taken me a few days to refill my script.  I can tell a huge difference in my hunger, and carb cravings when I do not take the glucophage.

Almost forgot to mention . . .now I take 2000mg of Glucophage daily.
melissakolman
on 1/28/12 11:52 am
Thank you for your entry. I have been contemplating bariatric surgery for 15 years however felt that there was more to my issue than eating poorly... Turns out that I have wonderful Blood Sugar levels so my fatigue and weight gain must be from overeating... Not so, I finally found a doctor that actually listened to me that I can't muster up the energy to get out of bed, to cook, to work...and knew that I wasn't depressed. Two mesely blood test explained the cognitive impairements and lethargy and huge amount of weight gain regardless of exercise or diet. Yep my insulin serum is 21 and my vitamin D was low. Okay, so I have insulin resistence which is not the same as Diabetes at all however they treat it with the same medications that they do diabetes II. I haven't experienced any major benefits from the meds, other than a lovely upset stomach, but it has only been a few days since I started them.

Insulin resistence is different, it doesn't matter what you eat, how much you, how much you diet. I am glad that I finally found out why I can go on a vegan diet, daily exercise and gain weight-not logical at all. It makes sense now. So, I am left with the thinking that bariatric surgery is not logical because my pancreas is still going to be malfunctioning even after surgery because it is not insulin resistence diabetes. It appears that a majority of diabetics can stop their meds and not have to return unless they are making poor choices in foods-thats what I have read. But this metabolic disorder is a different breed? Its confusing. By the sounds of things, this is a disorder that will be with me for life regardless of what I eat or how much exercise I get-however, I have noticed that it seems to be a little bit better if I only eat a small amount (for the most part). So, the only benefit I would have in getting the bariatric surgery is to control portion sizes so that I don't fall asleep every time I eat, but it won't fix my problem with the insulin resistence-however it will probably ensure that I do not make myself vulnerable to becoming diabetic.

I apologise, I am trying to figure out what it is that I can do to regain my life with the least amount of trauma and to better enable myself to successfully acquiring motivation and better health. It sounds like I will have to be on the metformin/glucofag meds for life, so it is bettter to see if I can eat smaller portions and eat more frequently to try to assist the metabolism in working better. The question is can I achieve this balance with or without the surgery. Thank you so much for listening to me and thank you so much for sharing your story.
myminime
on 1/28/12 12:28 pm - Eugene, OR
 I would discuss this with your endocronologist and a bariatric surgeon because you might be surprised!  The RNY does alter how your body interacts with your pancreas.  I'm insulin resistant as well, and I've done well after my RNY.

Not saying it's an end all solution, but it's still worth discussing.  My endocronlogist drew some lovely pictures to explain the process to me - too bad I'm not nearly as eloquent!
HW:  255  SW:  225.7  CW:  156.3

    
melissakolman
on 1/28/12 11:56 am
Insulin Resistance is not Diabetes, however you can be an insulin resistent diabetic. See the post a couple people down, there is a lady who has gone through it!
mhereford
on 2/19/10 5:20 am - Louisville, KY
I am Type II Diabetic.  Prior to surgery I took 200 Units of Lantus (long-acting insulin) and 45 Units of Apidra (short-acting insulin) plus 4/1000 mg of Prandamet  (Prandia/Glucophage combined) twice a day and 5 mg of Onglyza which is supposed to stimulate the pancrease to generate more cells.  With all these meds, I was doing good to keep my blood sugar under 140.

I came home from the hospital with a prescription for liquid Glucophage (500 mg) twice a day.   That's it!  My blood sugar usually runs normal since surgery, so I don't need to take the Glucophage either.
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