Question:
What exactly is dumping?
I read about people 'dumping' and it does not sound good. What exactly is dumping, what causes it and what can you do to avoid it? — Susan M. (posted on August 2, 2001)
August 2, 2001
Dumping syndrome is usually divided into "early" and
"late" phases - the two phases have separate physiologic causes
and will be described separately. In practical fact, a patient usually
experiences a combination of these events and there is no clear-cut
division between them.
Early dumping is caused by the high osmolarity of simple carbohydrates in
the bowel. The various types of sugar all have small molecules, so that a
gram of (for example) sucrose has MANY more molecules than a gram of
protein, creating a higher concentration (number of molecules per cc) from
simple sugars than from other foods. This matters because, inside the body,
fluid shifts will generally go toward the higher concentration of
molecules. So, if a patient consumes a bite of milk chocolate (lots of
sugar), when it gets to the Roux limb it will quickly "suck" a
significant amount of fluid into the bowel. This rapid filling of the small
bowel causes it to be stretched (which causes cramping pain). This also
causes the activation of hormonal and nerve responses that cause the heart
to race (palpitations) and cause the individual to become clammy and
sweaty. Vomiting or diarrhea may follow as the intestine tries to quickly
rid itself of this "irritant."
Late dumping has to do with the blood sugar level. The small bowel is very
effective in absorbing sugar, so that the rapid absorption of a relatively
small amount of sugar can cause the glucose level in the blood to
"spike" upward. The pancreas responds to this glucose challenge
by "cranking up" its output of insulin. Unfortunately, the sugar
that started the whole cycle was such a small amount that it does not
sustain the increase in blood glucose, which tends to fall back down at
about the time the insulin surge really gets going. These factors combine
to produce hypoglycemia (low blood sugar) which causes the individual to
feel weak, sleepy, and profoundly fatigued.
Late dumping is the mechanism by which sugar intake can create low blood
sugar, and it is also a way for gastric bypass patients to get into a
vicious cycle of eating. If the patient takes in sugar or a food that is
closely related to sugar (simple carbohydrates like rice, pasta, potatoes)
they will experience some degree of hypoglycemia in the hour or two after
eating. The hypoglycemia stimulates appetite, and it's easy to see where
that is going....
The reason that sugar does not cause dumping in non-operated people is that
the stomach, pancreas, and liver work together to prepare nutrients (or
sugar) before they reach the small intestine for absorption. The stomach
serves as a reservoir that releases food downstream only at a controlled
rate, avoiding sudden large influxes of sugar that can occur after a
Roux-en-Y. The released food is also mixed with stomach acid, bile, and
pancreatic juice to control the chemical makeup of the stuff that goes
downstream and avoid all the effects outlined above.
Obviously, surgeons consider dumping syndrome to be a beneficial effect of
gastric bypass - it seems to be important to provide quick and reliable
negative feedback for intake of the "wrong" foods. In practice,
most patients do NOT experience full-blown dumping more than once or twice.
Most simply say that they have "lost their taste" for sweets.
— Julia M.
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