Question:
Cushing's Disease (hypercortisolism) prior to surgery?

I have a dear friend who is fighting for her life in the hospital as I write this. She was diagnosed with diabetes and thyroid problems (both of which are indicators of Cushing's Disease), however she was not tested for Cushing's prior to gastric bypass in November. Cushing's causes a weakening of tissues in addition to a myriad of other life-threatening problems. She is now on a respirator and may not survive. Please talk to your surgeons if you have these same symptoms prior to surgery. If they are aware of it before surgery, they can treat the Cushing's and make sure the cortisol in your system is at a normal level, which may decrease your chances of endangering your life with WLS. Does anyone know if it is common to test for Cushing's pre-op?    — Christie S. (posted on March 13, 2002)


March 13, 2002
Usually a Dr can tell if you have cushing's by looking at you. It has a very distinctive body type, very large stomach and very spindly (NOT normal thin, but thin thin) arms and legs. I believe there is also usually a fat hump in the back, though pcos can also cause a buffalo hump. I don't believe the test for cushing's is common. One problem though, is even with wls it's very difficult to lose weight with cushing's or prader willis. I hope your friend gets better.
   — Becky K.

March 13, 2002
here is a site about cushings http://neurosun.medsch.ucla.edu/Diagnoses/Pituitary/PituitaryDis_8.html so sorry to hear of your friend being so down... I will keep her in my prayers! Barb
   — Barbara W.

March 13, 2002
Hi! I am SOOO glad you posted this! I am undergoing testing at this time to have WLS. My DR ordered a Cat scan of my adrenal glands as my cortisol levels are abnormal. (high) How they detected this in me was due to my blood sugar being low. One of the causes of this is an elevated cortisol level. The DR thinks I may have tumors on my adrenal glands, but has not mentioned anything about Cushings Disease or Syndrome. Due to the research I have done on this, I have been concerned! I do know the DR told me this has to be taken care of before WLS. Looks like I have some questions to ask. Had my Cat scan a few days ago...Waiting on the results.
   — ScatCat

March 13, 2002
I'm sorry to hear of your friend's condition. There is a blood test to determine the amount of cortisol in the blood which will alert the physician to a variety of diseases/disorders depending on increased or decreased levels. It is a test to measure the serum cortisol which is performed on patients who are suspected to have hyper- or hypofunctioning adrenal glands. For this test, blood is usually collected at 8 a.m. and again at around 4 p.m. The 4 p.m. value is anticipated to be one-third to two-thirds of the 8 a.m. value. There are, however, drugs that can increase or decrease levels, and physical and emotional stress can elevate cortisol levels. I switched surgeons and procedures before I actually had my surgery. My first surgeon did not require an endocrine evaluation. The second one did. This was one of the tests performed to rule out any problems with my endocrine system which was cause my weight gain. I think all surgeon's should require this.
   — gracie30269

March 14, 2002
My endocrinologist tested me for Cushings before he would refer me to the surgeon. He said there are two ways to test for it: taking a cortisol pill and having blood drawn exactly 8 hours later or collecting all of your urine for a 24 hour period and taking that in to the lab. I am so sorry your friend wasn't tested first and I really wish her the best for a speedy recovery.
   — Susan B.

March 14, 2002
I am so sad to say Leigh lost her battle last night around 11:00 p.m. I felt it was important to post this question so that others will research this condition. Although it is not common, the chances of surviving WLS with this disease seem slim. Please spread the word to others with multiple symptoms including but not limited to thyroid problems, high blood sugar/diabetes, excess hair growth on face, neck chest abdomen and thighs, buffalo hump above the collar bone, weight gain in face (moon face), and/or easy bruising and purplish stretch marks. Leigh had an amazing lifeforce and she will be terribly missed. She is in God's hands now.
   — Christie S.

March 14, 2002
I am so sorry to hear about the death of your friend. You may have saved my life with this post. I can't thank you and your friend enough. I am so sorry for your loss.
   — ScatCat

March 14, 2002
I'm sorry to hear about your friend. In answer to your question, when I had my blood gasses done, the endocrinologist also ordered a test for Cushing's for me. He ordered it because I have a tendency to bruise extremelly easily, and he just wanted to rule Cushing's out as a cause. If I hadn't had the bruising issue, the Cushing's test would not have been a normal part of the pre-op testing.
   — Kathy J.

March 14, 2002
I just wanted to say that testing for this is rare. After viewing another post where the symptoms were mentioned, I spoke with my doctor about this disease. My daughter is having tests done this week to rule out Cushings. If I had not seen the posts, I would not have been aware of this disease. Good Luck everyone.
   — Beffy W.




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