Question:
I am one month post-op and my depo shot is due...

would it affect my wieght loss? Because when I was on it for the 1st time back when i was 16 I gained about 60 lbs from it....    — V. Millbrook (posted on October 3, 2006)

October 3, 2006
The depo shot is funny.... I was able to lose 50 lbs while on it.... do it think it is directly from the shot...no. I think it is possible that you just gained the weight anyway. Yes, a sideeffect of depo is that it can modestly increase your appetite but if you've had surg it shouldn't be a big deal. If you ask most doctors about the pill/depo provera they will say that people who gain or lose a large amount of weight are doing something else...i.e. eating more...the depo itself doesn't cause the weight gain. I think if you are vigilant to look for any changes and continue to eat good choices you will be fine. Best wishes!
   — SteffieBear15

October 4, 2006
I've seen so many people who have gained weight on depo. From what I have seen, it almost seems to induce or mimic PCOS (polycystic ovarian syndrome). The "symptoms" from it are very similar to what I have experienced with PCOS and I can't imagine voluntarily doing that....but that's me! Consider that depo is a hormone and changes your hormone levels. Insulin is a hormone and is affected by other hormone levels. If it made you gain weight before, I would think it could again even after surgery....or at least slow loss, because it *appears* that it changes the metabolism. Just be aware of that and maybe consider a different kind of bc for awhile.
   — Dinka Doo