Question:
Do I have to stop antidepressants prior to surgery or during liquid phase?

I've taken antidepressants for several years & a few years back when I was switched from Zoloft to Lexapro, I had a terrible time- aka breakdown almost. Will my meds be suspended during the days before or after surgey? Are they liquids available or injections, so the depression doesn't attack me when I cannot swallow pills? Thank you    — dawnie125 (posted on June 16, 2007)


June 16, 2007
You didn't say whether your surgery will ber lapband or gastric bypass RNY. But I work for a bariatric program and what I get from our Doctors is this: most pills will be ground up and taken in stirred in sugar free jello, the best advice I can give you is first speak to your Doctor, next your pharmacist and make sure the pills can be crushed, some can not, also if it is RNY surgery pills intened for extended release sometimes have to be replaced with pills that are not and take more often. I had open RNY 14 years ago and no one addressed pills with me either, I started taking hormone replacement before I had hot flashes so I did not know what one was. I was told nothing solid by mouth for 4-6 weeks I took that to mean pills. I was in the hospital for 7 days, about the 3rd day I felt like bugs were crawling on me I was sick to my stomach mad at the world and being a royal B to my bestfriend staying with me. Lucky for me a older nurse came on shift and took one look at me and asked" are you on hormones?" To which I replied roughly "yes but I can't have anything solid so I have not taken them!" She left and can back with a hormone patch, slapped it on my backside and that evening I felt like myself again. I thought I was going crazy. I had a good little talk with my Doctor when he made rounds about educationing his patient prior to surgery about home meds and what to do about them in house and at home. It was a learning experience, alot of meds you can take in liquid like pain meds but some are not and you crush them until you are back on solids and if they are famous "horse pills" you may still need to break them in half. Talk to your Doctor and the pharmacy. Good luck!
   — DonnaB.

June 16, 2007
There are drugs out there that come in liquid,topical,on the togue dissolvable, chewable,etc. I could not grind up my meds,they were so bitter,and since my intake was only 1-2 ounces at that time,the taste lingered forever,it seemed! I contacted a pharmacisit & told them my dilemna & they checked the PDR to see if 'my' meds came in other routes. And I spoke with the different doctors after I found solutions & changed my meds accordingly. I only had to change one med to another,and the change has been satisfactory. I would have done one thing differently,tho. I would have done all this before I had the surgery I was fatigued already, after surgery,besides all the phone calls & running back & forth to the pharmacy for new scripts. I hope that this helps
   — peacelovecat

June 16, 2007
I have taken lexapro for years and never missed a dose, prior to surgery or afterwards. They are very small pills and quite easily swallowed. Good Luck.
   — Kristi S.

June 16, 2007
Dawn, you pose a really good question, but you need to get with your surgeon on this one. I don't know if a liquid form is available, but I can say that they will do what they can to keep your medication cycle as normal as possible. Just keep in mind that you may need less of this medication after surgery. You will absorp only so much, and as your body loses weight, you will need less for the same affect. This will mean changes along the way. You have to really listen to your body and know the symptoms of depression so you can pick up on them as you change in weight. Also, you may find that if you get into a really good exercise routine, that you are really helping the body deal with depression and you may want less medication as well. It is amazing what the body will do for you if you work it out. Getting all that stress out in sweat and fatigue makes a huge difference. I don't know why you deal with depression and I won't dare to guess, but I hope that those issues that have brought you down that you have dealt with them prior to surgery. I will tell you that many men and women who had depression issues prior to surgery and did not deal with them can see a significant increase in depression and problems because they didn't face their fears or pain. They didn't have food to run to any more and that stripped them of their hiding place, which can cause a lot of problems along the way. Please be sure you are ready for these changes and are doing all the mental things you can to prepare for surgery. It will be a better outcome for you if you do, even if the pain of dealing with the past is hard for now. Take care and I wish you well. Patricia P.
   — Patricia P

June 16, 2007
my surgeon said he wanted everyone on anti depressants to never miss a dose. he is the head of the ASBS
   — bob-haller

June 17, 2007
Those of us who suffer from clinical depression are often extremely dependent on our antidepressants. This is not because we haven't dealt with issues, but because we have a metabolic issue with neurotransmitters that don't function properly. Surgery of any type WLS surgery, specific are put us a risk for depressive episodes. It is very important that your meds are continued. Check with your surgeon and phsychiatrist to determine the the best way to ensure your mental and physical health during the post-surgery period and as you continue through this life-changing process. I take Cymbalta, which is a time-released medication, as well as others. The Cymbaltha is a capsule and I have not had any issues swallowing it. I take a couple of others that are small tablets. One of the things you'll need to do is to work on scheduling your meds. I take one at a time at the bottom of each hour. I am working closely with my phsychiatrist to monitor my antidepressants and maintain the "sanity" I worked so hard to win back. I also see a counselor every other week to address issues I have that are related to my weight and my relationship with food. It would probably be a good idea to have your phsychiatrist work directly with your surgeon to determine how to best manage your medications to protect you as you navigate your post-surgery journey. This way there won't be guess work about absorbtion rates, appropriate substitutes, etc.
   — Barbara C.

June 17, 2007
WE ARE NOT YOUR SURGEON!! It'd be BEST to check with them or/and your Primary Doctor.
   — Michael Eak

June 17, 2007
I also take Lexapro. I took it all through the liquid phase diet up until the morning of surgery (05/14/07), once in the hospital they gave me the liquid version, and then the first day home I was right back on the pill. So if your experience is anything like mine, you should be fine and not even miss a dose. Good luck.
   — StacyL79

June 18, 2007
I have taken antidepresants for a long time. I did not stop even preop or postop and inbetween. I cut them in smaller pieces. I have heard there are liquid forms of some medications. Who ever prescribs these antidepresents is who would know for sure. None of my medications were stopped pre, during, or post op. I have also experieced the breakdown deal. But I am so glad I did this surgery and working with my team thru out has helped me to live and want to live. I wish you great success with your new way of life. I had positively had no problems thru out. Email me and let me know how it went...mTackett
   — mtackett




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