Is it possible to gain seven pounds in a week?

I have gained seven pounds in a week and can not understand why. I exercise at least three times a week for 45 minutes to an hour. I was taking demadex for fluid retention but it seemed like lately they were not working like they use to. I call my specialist that I see for my lupus and asked if he could prescribe something else. He gave me lasix, 40mg. I took 80mg the first day and nothing extra happened. It is like the fluid pills are not working like they use to. Should I have blood work done to check on my kidneys? There are some days I do not get in 64oz of water or fluid but for the most part I do. Please help.

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