I take SAMe for depression. As a very unstable ''drug'' it is enteric coat.

It needs to get to the lower intesteines for effectiveness. Any professionals out there who can give me ideas on what to do about this. I am thinking rectal dosing. Haven't found someone willing to respond. I do not want to go for 4-6 weeks without the SAMe with risk to increased depression after the surgery. I am having surgery this Friday morning....kinda doing this on my own, my ''S/O'' with take me to the hospital, but leave me until it is time to go home again (up to a week). The hospital is 100 miles from home. Thanks for thoughts and ideas...

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