Charly Horse in Lower Legs Two Nights in a row!

Help! I'm six mos. post/op Open RNY, 94 lbs down, so far.(I'm about 15 lbs from goal). The last two nights I've been waking up in the middle of the night with a charlie horse in my calf... two nights ago the left calf, last night the right calf... I haven't had this happen since I was pregnant, and that was years ago. Is this a vitamin or mineral deficiency? What can I do or take to prevent this from happening again? My labs came back normal last month... I take a chewable multi vitamin daily, and get B-12 shots... the last one being last week. These charlie horse episodes are so severe that I hurt all day the day following an episode. I have not changed anything in my normal routine or exercise to possibly bring these on...

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