antidepressant sr

Hi all,

Had vsg in Oct 2011 that had to be converted to rny Oct 2015 due to GERD.

I have been on Wellbutrin SR for a number of years. I have had some life issues that have thrown me into a major depression. My Psychiatrist says sr or xls do NOT work due to absorption issues so I have probably not been getting any benefit. Has anyone else experienced this? I have tried other antidepressants with various bad side effects which is why I am on Wellbutrin 150 sr 2x. He is trying 2 100 immediate release which is less than what I was on because he does not want to overdue if I have not been getting any from the sr. If you could add some thoughts on this I would greatly appreciate it. Feeling desperate.

I was told that I might have issues with Cymbalta. My therapist changed my med from 1 60mg cap to 2 30mg caps. I have been doing great.

Good luck, I hope you find something that work for you!!!

Thank you for your reply. Sounds like he felt one pill with that much mg would be gone before you could absorb it but you would get enough in 2 doses. My problem is because with Sr you can not cut it in two and it's apparently gone before it releases the full dosage.

The little beads inside the capsule are slow release. I take the 2 together in the AM, but if I started to feel increasing depression I could take 1 cap in am and 1in the pm.

Is your med available in a smaller dose but you could take it maybe 2-3 times a day??

That's what we are trying. Immediate release crushed like a chewable baby aspirin in 2 100 mg. May have to bump up to 3. Thanks.

I take Wellbutrin SR and I haven't noticed an issue. If I'm not absorbing it well then my depression is better. My Psych Didn't think it would be an issue but it would seem like it should be. I see my surgeon next week and plan on asking about that. I hope you find some relief.

Found this out when a psychiatrist came to the hospital where my daughter works and they were advised bariatric patients should not be prescribed Sr or xl due to absorption issues and that a lot of bariatric surgeons are either unaware or not addressing the issue. Also if 90% of serotonin is produced in the gut what happens when our gut is the size of an egg? Asked my surgeon and he said no studies have been done on that issue. Just an issue with those of us who experience serotonin related depression.

Your stomach is still in your body, it hasn't been removed (as in the VSG).

I had the vsg and then the Rey due to herd. So no it is no longer there.

Interesting topic; the absorption (or lack thereof) of psych meds. I have been stable on a ****tail of lamotrigine, seroquel xr and klonopin for a few years now. Minimal breakthrough mania and depression. Depression broke through big time at the end of January, and I have been struggling. Finally got my new pdoc to prescribe Paxil as an adjunct to the above ****tail, and we will see. But as it's said here in the the thread, if seratonin is produced mainly in the stomach and we now have an egg sized stomach, what is the recourse?