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Be careful - the drug (Belviq) is the subject of a FDA investigation right now as there are serious risk and safety concerns associated with the product.
Living larger than ever,
My Bariatric Life
Thank you for sharing the link.
In my opinion, there are some inacurracies in the article that you are referring to.
The article states: "Lorcaserin has had an effect on the serotonin receptor, the origin of theheart problems associated with phen/fen"
This statement is misleading. There are three receptors for serotonin, the 5HT2C receptor which Belviq targets specifically, and the 5HT2A and 5HT2B (fenfluramine) which Belviq does NOT target. Fenfluramine, which is the part of Phen/Fen that caused heart valve damage, targets the 5HT2B receptor.
Here is the FDA briefing document on Belviq: http://www.fda.gov/downloads/AdvisoryCommittees/CommitteesMe etingMaterials/Drugs/EndocrinologicandMetabolicDrugsAdvisory Committee/UCM303198.pdf
"Lorcaserin preferentially activates 5HT2C with 8- to 15-fold greater potency compared to
5HT2A, and 45- to 90-fold greater potency compared to 5HT2B" "Arena additionally demonstrated that based on functional activity across four in vitro assay platforms, lorcaserin grouped with low-potency 5HT2B agonists that are not known to be associated with clinical valvulopathy. By comparison, compounds known to cause clinical valvulopathy such as nordexfenfluramine and pergolide showed substantially higher 5HT2B receptor potency in these assays" "The 2011 receptor potency data provides supportive evidence that off-target activation of the 5HT2A or 2B receptors is unlikely at the proposed clinical dose of lorcaserin (10mg bid)" The article that you have enclosed also states "The medication should not be used by pregnant women". The FDA's opinion is that pregnant women should NOT think about losing weight until after they give birth. The fetus needs nutrients and depends on his mother in order to get the nutrients. The author should have done a lot more research before posting the article.
Agree with you completely... And yeah, sucking out the food you have eaten is no differ than binging and purging... Nothing good can come of that.i dealt with bulimia for years and it was difficult to overcome.
Living larger than ever,
My Bariatric Life
Thank you for your reply. so e of the non surgical weight loss interventions are extreme, indeed!
however, I do not believe Belviq to be a good solution. The gravity of the side effects of lorcaserin are worth noting. You may read more here http://www.healthcentral.com/obesity/c/276918/154206/lorcaserin-loss
Living larger than ever,
My Bariatric Life
Well said!
Living larger than ever,
My Bariatric Life
A rant, by me.
I was obese my entire life. I too did hundreds and dad diets...I too could walk at a very fast pace...I too lost and regained probably thousands of pounds!
Then one day I made some changes. I have *stayed consistent* in my diet and activity and I have lost 160 lbs. here is my secret I LET GO OF MY EXCUSES! I LET GO OF MY "I CAN'TS" and then I frickin' did it. Period.
I run 5 miles or more a day...usedta couldn't! I started where I was and worked my way to where I am. None if it was easy. I earned this...YOU can too.
Disclaimer: this is not an anti surgery rant as I support the choices of others. This IS a rant about people asking how I have lost and maintained my weight only to throw the "oh I could never do that" card up. You can if you choose!
The problem with Victoza is that it is injectable AND has nasty side effects including pancreatitis.
The tongue patch seems to be too extreme.
A new drug that has just been approved by the fda called Belviq seems to be promising. Drugs.com has many reviews by individuls that have tried it and it seems t work pretty well. It also seems to affect mood in a positive way abd to help with smoking cessation. http://www.drugs.com/comments/lorcaserin/belviq.html
Since this post is 3 years old, how did you make out? Were you successful on the program? I am currently using Omni Drops and the weight is just melting away!! I can add you to the FB page, it's awesome!!! You can see how successful thousands of people are by using their products. Let me know!!!
