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hi... i also have RA and am and RN so this is what i have experienced and know. it does depend on your particular medications. for embrel.... the drug leaves your system in one week... thus you have to take the drug weekly. my mom who takes this drug and just had the vsg was instructed to stop the injection one week prior to surgery. she decided to give it two weeks. and then was told she could continue 3 weeks out but gave it 4 weeks to be on the safe side. methotrexate does have a longer effect in your system. my mom is not on methotrexate so i do not know what the RA doctor would have said. so maybe some others will have info. just a side note.... i am steroid dependent. i have been on medrol for 18 years. so with steroids if you are dependent you are not able to stop abruptly so for sure take with your surgeon for specifics. hope this helps and best wishes on your future surgeries. and congratulations on your successful weight loss. kelly