Why NSAIDS can harm the pouch...

(deactivated member)
on 3/13/06 7:14 am - Warner Robins, GA
I wanted to share this info with you all about why NSAIDS can be dangerous for us. Contrary to popular belief, it is not just that they are "pouch burners". It goes deeper than that. According to an article published in the June 1999 New England Journal of Medicine, NSAIDS, once absorbed into the blood stream cause a chain reaction that affect the prostaglandis and this in turn reduces the production of mucus in the GI system. THe mucus is what lines our GI system and protects our pouch and instestines from damage. If the mucus production is reduced, this would allow ANYTHING, including eating something with too sharp of an edge or foods that are extremely spicy, to inadvertently begin a marginal ulcer. The best answer is to avoid NSAIDS. Taking a H2 receptor drug such as Prilosec, Prevacid or Nexium is only a band-aid and no guarantee that it will protect you. We are at risk for marginal ulcers any time we take an anti-inflammatory medication. Hope you all find this info useful. I was one that thought that NSAIDS were just pouch burners, but now understand how they work. Hugs, Tonya
tammygunter
on 3/13/06 11:13 am - 'Jefferson, GA
Thanks Tonya Tammy G
Feelin Fine
on 3/14/06 11:50 am - Atlanta, GA
Good Info! Thanks, Rozzy
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