Lab results

Hi all, I’m just posting my ‘iffy’ results rather than everything.  I’ve been referred to an endocrinologist for my high serum alkaline phosphatase – not sure what that’s all about.

Transferrin saturation is 0% - WTH?  Plus I have high Transferrin??  I am seeing a haematologist in a couple of weeks and he seems to be OK with the idea of giving me infusions (PCP was really against them, but I fought my corner and got referred).

Serum alkaline phosphatase level 155 (30-130) H
Corrected serum calcium level 2.14 (2.2-2.6) L
Serum iron level  8 umol/L (12-27) L
Transferrin 999g/L (2-3.4) H
Transferrin saturation 0% (20-60) L

PTH is back in range 6.5 (1.6-9.3)
Vit D OK @ 116 but no reference range!!

Zinc results still pending.

I’m a bit baffled, so I appreciate your thoughts and feedback.

TIA

Alkaline phosphatase is a measure of liver function along with ALT and AST.  A very high number could indicate that there is a problem with liver function.

Transferrin and transferrin saturation, I believe, is the amount of free iron in the blood.  Below is a description:

Transferrin saturations of less than 20% indicate iron deficiency, while transferrin saturations of more than 50% suggest iron overload.

The terms transferrin saturation and iron-binding capacity, saturation, are interchangeable; however, in the last several years, this value is most commonly referred to simply as the transferrin saturation. This also minimizes confusion with another frequently used value, the iron-binding capacity, when determining a patient’s iron status.

The reference range of the transferrin saturation varies by age, as follows:^[1]

• Adults: 20%-50%

Your Vitamin D levels are awesome!!!  Anything over 70 is what we DS'ers are targeting! Congratulations on being your own advocate and getting that referral!! WTG 

Thanks. BTW liver function test came back fine, I don't remember the numbers off hand. I'll see what the endo says in February. I just wanted to know if there was anything I should do in the meantime, but nothing seems to be jumping out at folk.

Thanks for positing your labs.  I learn so much from these round robins on what the numbers represent.

Yes, I'm working at trying to understand as much as I can too.  I like to see my PCP forearmed with good info.  I pushed for a hematology referral a couple of months ago and see the hema again just before Christmas, thanks to everyone on here saying to self advocate (I wrote a letter and that got some action).  One PCP I saw said my 'iron' labs were "fine"... seriously??