Uh oh....high blood sugars!
Not sure about there being no risk of ever developing type 1 diabetes, but then I'm not an endocrinologist. Measuring total insulin levels and/or c-peptide levels (a non-usable by-product of insulin) discern if you if you're making your own insulin or not.
If you are making insulin and your glucose levels are high then that's insulin resistance (metabolic syndrome and/or type 2 diabetes).
If insulin and c-peptide levels are zero, then you're not making insulin any longer and that is type 1 diabetes.
Many type 2's "burn out" with time and require insulin replacement later in the disease process or need additional insulin to overcome their resistance. Whether they are labeled type 1 or type 2 diabetics depends on the specialist and the current literature.
I'm not sure which test your SIL's had.
If you are making insulin and your glucose levels are high then that's insulin resistance (metabolic syndrome and/or type 2 diabetes).
If insulin and c-peptide levels are zero, then you're not making insulin any longer and that is type 1 diabetes.
Many type 2's "burn out" with time and require insulin replacement later in the disease process or need additional insulin to overcome their resistance. Whether they are labeled type 1 or type 2 diabetics depends on the specialist and the current literature.
I'm not sure which test your SIL's had.
I could be wrong and the study might have been testing the actual testing methods....if that sentence makes any sense. The SIL's are poor historians, as you medical peeps say, so it's hard to tell. I *thought* they had, oh I dunno, antibody or genetic or some kind of already-known testing to determine whether non-type I SIL was at risk of type I.
In actuality, it's possible that type I SIL is a turned-over type II who was just utterly clueless about what she had going on until she got so sick it couldn't be ignored any more.
To make matters even more interesting to the researchers, there is a bona fide type I SIL (not a triplet) as well, and the only NON diabetic in two generations on both sides (going back to their grandparents and all the siblings) is my MIL. Well, and Mr. EN so far, so that makes two. But if he follows the pattern of the rest of the family, as he appears to be with the changes in his body composition and whatnot, that type II is at most ten years away for him.
I had the whole shebang finally tested at one time during my preop clearances. The insulin and c-peptide levels were so far gone that the endo doc gave me little hope of getting off insulin, much less becoming diabetes-free. He couldn't justify billing insurance for a glucose tolerance test, so I dissolved a bunch of glucose tablets and did my own. My results impressed him enough to agree with me that I was "probably" cured LOL.
In actuality, it's possible that type I SIL is a turned-over type II who was just utterly clueless about what she had going on until she got so sick it couldn't be ignored any more.
To make matters even more interesting to the researchers, there is a bona fide type I SIL (not a triplet) as well, and the only NON diabetic in two generations on both sides (going back to their grandparents and all the siblings) is my MIL. Well, and Mr. EN so far, so that makes two. But if he follows the pattern of the rest of the family, as he appears to be with the changes in his body composition and whatnot, that type II is at most ten years away for him.
I had the whole shebang finally tested at one time during my preop clearances. The insulin and c-peptide levels were so far gone that the endo doc gave me little hope of getting off insulin, much less becoming diabetes-free. He couldn't justify billing insurance for a glucose tolerance test, so I dissolved a bunch of glucose tablets and did my own. My results impressed him enough to agree with me that I was "probably" cured LOL.
Thanks Doc! I got the post too late to have them added but I'm going to call my PCP and ask her to run those tests. I'd rather be safe than sorry.
My fasting stick this morning was 78. It was in the low 120's for at least 3 days though. I wonder if I was trying to get sick? I also tested 1 and 2 hours after eating and my high at 1 hour was 152 and 2 hours was 115. Not much fluctuation there so it was just high in the morning.
I should have my annual labs back in the next day or so.
My fasting stick this morning was 78. It was in the low 120's for at least 3 days though. I wonder if I was trying to get sick? I also tested 1 and 2 hours after eating and my high at 1 hour was 152 and 2 hours was 115. Not much fluctuation there so it was just high in the morning.
I should have my annual labs back in the next day or so.
EN I think you might be thinking of trialnet they are an organization that is trying to find a cure with research and they also do testing of siblings and keep a data base of the blood work to see if they can find the specific genetic markers for T1. When they test siblings and family members of a T1 they are looking for 4 anti-bodies markers. The more markers that someone test positive for the higher the chance they will end up with T1. There are some that will test positive for years and never end up with T1. We currently get our youngest daughter tested every year for the markers since her big sister is T1 and the earlier its caught the better for trying to keep a honeymoon and try to keep some of the beta cells working for longer. Thankfully there have been no markers show up yet for us.
Krazydoglady is right too there is type 1.5 also know as lada diabetes which is latent autoimmune diabetes. Lada is usally misdiagnosed as T2, due to the fact if you get it as an adult mentality of most health care professionals it must be T2.
Krazydoglady is right too there is type 1.5 also know as lada diabetes which is latent autoimmune diabetes. Lada is usally misdiagnosed as T2, due to the fact if you get it as an adult mentality of most health care professionals it must be T2.