Will the removal of skin affect my Depo

I get my Depo shot in the upper part of my butt. I'm scheduled to get it two weeks before I go in for Plastic Surgery. My PS will be removing skin from the front AND the back. I'm pretty sure the common term is Lower Belt Lift, though my surgeon calls it something I can't pronounce. Will the removal of the skin from where my Depo is injected also remove the Depo or make it not work as well? Thanks - I'll ask my Gyno, too, but thought I'd post it here first :)

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