I need to know if there are drawbacks to the great decrease in ghrelin.

I am considering vertical sleeve gastrectomy and am looking for detailed scientific research into the long term affects of having the decrease or elimination of ghrelin, which seems not to be dealt with. I do not have a great memory anyway, and I would hate to think I would extend my life with surgery only to get Alzheimer disease. I have read that "ghrelin plays a significant role in neurothrophy, particularly in the hippocampus and is essential for adaption to changing environments and the process of learning." I can't help wondering if there is not a huge rush to having this surgery while there is still so much unknown about the long term results. I hope I can get an answer to this as most I find on the internet is very technical.

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