What is the deal with Extended release medication?

Can we or can't we take extended release medicine? I have heard many times that we cannot take them, but I have not heard why. Is this just a myth? What facts do we have that show us that we cannot take this type of medicine? A web site or medical article stating this would be greatly appreciated. People keep saying that we can't take it, but noone has ever backed it up with some sort of concrete reasoning. Any help on this matter would be a great benefit to me. Thank you, Mary Beth

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